5250 Gas/Liquid Chromatography-Triple Quadrupole Mass Spectrometer (GC/LC-MS/MS)

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The 5250 gas/liquid chromatography-triple quadrupole mass spectrometer is an automatic switching mass spectrometer system that integrates EI and ESI dual ion sources. It connects gas chromatography and liquid chromatography on the same triple quadrupole tandem mass spectrometer to achieve automatic and rapid switching between the two analysis modes. It realizes GC-MS/MS and LC-MS/MS working modes on one mass spectrometer to meet the growing testing needs in the fields of food and drug, environment, and third-party testing.

DESCRIPTION

Performance advantages

Dual-mode dual-core, one system can realize GC-MS/MS analysis and LC-MS/MS analysis

E-Spray ion source, ensures efficient and stable LC-MS/MS analysis;

The gas-gas interface and EI ion source without cold spots throughout the process ensure efficient transmission and efficient ionization of GC-MS/MS samples;

Innovative dual-channel ion optical design, compatible with dual-channel ion transmission, with excellent sensitivity;

The 90-degree deflected GC injection channel effectively filters unionized neutral particles, avoids contamination of the back-end quadrupole mass analyzer, ensures that the instrument has lower background noise in GC-MS/MS mode, and can ensure the long-term stability of the mass analyzer;

The dual-orthogonal LC injection channel, combined with Step Scan ion transmission technology, has higher ion transmission efficiency;

The innovative axial acceleration collision cell technology greatly improves the collision efficiency.

A mass spectrometer workstation has two analysis modes

The mass spectrometer workstation not only supports the functions of LC-MS/MS mode and data analysis and acquisition processing, but is also compatible with the operation of GC-MS/MS mode, realizing automatic and fast switching between the two analysis modes. The powerful one-key automatic tuning and mass calibration functions reduce the complexity of instrument control and the threshold for instrument use.

Diversified core technology

Dual orthogonal E-spray ion source

Powerful ESI ion source, expandable APCI ion source;

Orthogonal to the ion transmission path, 90-degree deflection reduces the entry of neutral particles into the mass spectrometer and reduces noise;

Orthogonal and symmetrical dual-path desolvation gas based on flow field simulation, efficient solvent removal.

Ion interface

High-purity nitrogen backflush to improve desolvation effect and matrix tolerance;

Heating gas path, precise temperature control.

High-speed dynamic collision cell

Axial acceleration design allows ions to pass through the collision cell quickly, taking into account collision efficiency and transmission efficiency, and reducing cross contamination.

Pulse counting detector

90-degree deflection channel electron multiplier;

Innovative pulse counting detection technology, with higher signal response and lower noise.

Reliable multi-stage vacuum system

Multi-stage vacuum system based on molecular pump + fore pump;

Vacuum step transition, reduce pressure mutation and ion loss.

Perfect instrument control system

All gas circuits, voltages and heating have interlocking control to ensure equipment safety;

The vacuum system is independently controlled and has perfect self-protection. The system can be guaranteed to be normal even without software;

All gas circuits are controlled by MFC to accurately control all parameters.

Advanced gas phase system

Equipped with GC 2000 gas chromatograph, it adopts advanced electronic flow control system and microfluidic plate control technology. High-precision independent temperature control system and high-sensitivity detector, with flexible and friendly user interface, high-speed sampling frequency and signal processing speed, meet users’ requirements for instrument analysis ability, reliability, stability and advancement.

Intelligent instrument control, simple and easy to use

The host monitoring software is based on the intelligent system of micro-core processor architecture, equipped with an 8-inch fully laminated high-resolution capacitive touch screen and image, combined with self-diagnosis reminder, self-leak detection, carrier gas self-saving and other intelligent functions, reducing the difficulty of use and maintenance, and easily mastering the status of the instrument. The system innovatively adopts a multi-core collaborative processing architecture, and task instructions are automatically allocated according to the current load of each micro-core, greatly improving the response time, execution efficiency and stability of processing tasks, ensuring that the software still has a smooth operation experience after long-term operation.

Excellent chromatographic stability

The whole flow path of the whole machine adopts a new generation of high-precision electronic pressure micro-control, with automatic atmospheric pressure and temperature compensation, and with reliable injection port and column oven temperature control module, the system has better analytical reproducibility. In addition, in some specific applications, the target analyte has a high boiling point and strong adsorption, and the excellent repeatability of the system can be ensured by selecting a fully inert pipeline.

Application field

It is used in a wide range of fields such as food safety and traditional Chinese medicine, and it has high sensitivity and high stability in various occasions, and reliable data can be obtained. The control and analysis software are equipped with a workstation that strongly supports quantitative analysis.

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